Drupal's node_load() function fires a great deal of queries and functions. The more module you use, the more node hooks will be involved in this call. Wherever possible it is advised to avoid calls to node_load(). Instead, try to fetch the specific fields you need directly. Best example: Views. Using the Views module you can build a page that lists all nodes. Each item requires a node_load() call. To avoid this, switch to using Fields in Views instead and call the fields that you really need. Then use custom Views theming to output the data.
- Reduce the load on the Drupal stack